Concluding a low urine creatinine is not common or immediate in the general population. Doctors measure these values more frequently among people who already have kidney disease.
Creatinine is a biochemical parameter, blood and urine, which is strongly linked to the kidneys. For nephrologists, it is one of the usual routine tests used in the follow-up of their patients.
This substance is actually a waste of muscle metabolism. When muscle fibers work, they generate creatinine as a product that must be eliminated. The route of elimination is through the kidneys and urine.
Thus, we can track creatinine in blood and urine to measure them. In the blood we find it as waste newly manufactured by the muscle, and in the urine we measure how much of this waste is being expelled to the outside.
Although it is common that only blood creatinine is measured in general consultations, when kidney disease is suspected it should be combined with a measurement in the urine. For this purpose, the most suitable method is creatinine clearance.
By comparing the levels of the substance in the blood and in the urine, we can detect specific abnormalities. If we have low creatinine in urine and high in blood, then we suspect kidney failure.
Creatinine clearance
This useful analysis to detect low urine creatinine has different names: clearance, clearance or clearance creatinine. All denominations identify the same methodology, whose objective is to report how much creatinine from the blood the kidneys are filtering.
To arrive at the result, blood and urine samples must be taken. Urine is collected for a full day, 24 hours, and delivered to the laboratory for analysis.
The biochemist runs the corresponding techniques and then applies a formula called the glomerular filtration rate. This rate, which is a mathematical formula, measures the filtering power of the kidneys at this time.
Values are generally expressed in millimeters per minute, and are considered normal:
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